Acta Rheumatologica

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Abstrato

A Rare Cause of Iron Deficiency Anemia in Patient with Ankylosing Spondylosis

Sai Kiran

Hematological manifestations of Cobalt toxicity were Polycythemia, Leucopenia, and Thrombocytosis. Polycythemia is usually seen in patients who receive cobalt chloride tablets orally which induces HIF-1 alpha leading to increased erythropoietin levels. With chronic exposure can cobalt rarely leads to decreased expression of Divalent Metal Transporter 1 receptors in the duodenum. This causes decreased absorption of iron from the GI tract and the patient presents with Iron Deficiency Anemia.