Neeraj Kumar, Paras Singh, Ravindra Kumar Dewan, Neihenuo Chuzho, Shreya Chauhan and Khalid Umer Khayyam
The re-emergence of novel coronavirus variant has grappled the world and imposed a halt across the globe. Since, its identification as a novel pathogen, the SARS-Coronavirus-2 has caused more than 2 million deaths worldwide. This novel virus against which humans have vastly variable immune response is still expanding its reach all over the globe. Hence, it is really critical to understand the important facts about such a lethal entity. Here, in this review, we bring together the pieces of the puzzle to understand the origin, epidemiology, pathogenesis, prevention and treatment strategies of this novel disease COVID-19. Important references to the previous SARS-coronavirus have been made to better understand the re-emergence pattern. This comparison will also help us to understand the crucial drivers of such re-emergence and the important lessons that we need to learn for prevention of any such future outbreaks.
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