Arquivos de Microbiologia Clínica

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Fersis-Phage against Purulent-Inflammatory (Staphylococcal, Streptococcal) Pathologies

Gabisonia T, Giorgadze I, Topuria N, Chanishvili L, Nadiradze M, Chakhunashvili N, Katamadze T, Loladze M, Tamarashvili N, Alibega Svili M, Kalandarishvili T and Eliava T

The problem of prevention and treatment of infectious diseases in infectious and non-infectious clinics is one of the priorities in practical public health. The application of phage preparations, as antimicrobial medioprophylactic remedies against staphylo- and streptococcal infections seems to be an alternative to antibiotics and sulfonamide preparations. Pronounced tendency of circulating pathogenic bacterial strains towards reducing sensitivity to antibiotics, also caused by irrational use of the latter, further confirmed our decision to create a new phage preparation. Based on the conducted studies the new variant of Fersis, an active, multivalent phage preparation, consisting phages against staphylococci (S. aureus, S. epidermidis) and streptococci (S. pyogenes, S. viridians, S. sanguis, S. salivarius, S. agalacticae) causing oral cavity infectious diseases, has been prepared.