Arquivos de Medicina

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Neurogenic pulmonary edema in patients with acute severe brain injury: Pathophysiology and man

Sheehan T

In the context of critical care, this article will offer a narrative assessment of the data pertaining to theories, diagnoses, and treatments for neurogenic pulmonary edoema (NPE). Although the precise mechanisms causing NPE are still unknown, putative mechanisms for the condition include increased catecholamine release, increased vagal tone, and increased capillary permeability. This is known as the "blast injury theory" because it causes pulmonary vasoconstriction as a result. The diagnosis entails spotting pulmonary edoema symptoms in the presence of a brain damage, and the most effective treatment methods seem to be those that aim to preserve a normal physiological condition. Any acquired lesion to the brain constitutes an acute brain injury (ABI), which is a major global cause of morbidity and mortality. Twenty to thirty percent of people with ABI get lung damage. Despite being a significant complication, neurogenic pulmonary edoema (NPE) is frequently underdiagnosed.