Arquivos na pesquisa do câncer

  • ISSN: 2254-6081
  • Índice h do diário: 13
  • Pontuação de citação de diário: 3.58
  • Fator de impacto do periódico: 3.12
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  • Fundação de Genebra para Educação e Pesquisa Médica
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  • Laboratórios secretos do mecanismo de pesquisa
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Abstrato

New methods for studying cancer metastases using metabolomics

David Cruzado

Metastasis is accountable for ninetieth of deaths in patients with cancer. Understanding the role of metabolism throughout metastasis has been restricted by the event of strong and sensitive technologies that capture metabolic processes in metastasizing cancer cells. We have a tendency to discuss the present technologies out there to check metabolism in primary and pathologic process cancer cells and metabolic interactions between cancer cells and also the neoplasm microenvironment (TME) at totally different stages of the pathologic process cascade. We have a tendency to establish benefits and downsides of every methodology and discuss however these tools and technologies can more improve our understanding of metastasis. Studies investigation the advanced metabolic rewiring of various cells victimization progressive metabolomic technologies have the potential to reveal novel biological processes and therapeutic interventions for human cancers.