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Translational Biomedicine

  • ISSN: 2172-0479
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Abstrato

Phylogenetic Tree and Antigenic Shift Analysis of Hemagglutinin Gene of Influenza A Virus in H5N1 Strains Found in 2005-2007

Repon Kumer Saha and Md. Abdullah

This study brings the analysis of phylogenetic tree and amino acid sequences of Hemagglutinin (HA) from the influenza A virus that can infect a wide variety of birds and mammals. We have analyzed strains of three different years (2005, 2006 and 2007) of H5N1 from different country to see the antigenic shift patterns with respect to reported mutant positions of amino acids. We did not find the exact location where reported mutations are occurred. But we found similar amino acids near the reported mutated positions but we found similar mutations around the mutated position that may cause antigenic shifts.