Jornal Internacional de Desenvolvimento e Pesquisa de Drogas

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Abstrato

Synthetic Trends Followed for the Development of 1,2,3-Triazole Derivatives

Khan Mohemmed Faraz, Verma Garima, Akhtar Wasim, Marella Akranth, Alam Mohammad Mumtaz1, Akhter Mymoona, Husain Asif, Hasan Syed Misbahul, Shaquiquzzaman Mohammad and Haider Syed Rashiduddin

1,2,3-triazoles find their application in the diverse areas of medicine. Enough literature is available demonstrating antibacterial, antifungal, anticonvulsant, antiviral, antidiabetic and antimalarial potential. Owing to their wide application, scientists across the globe are engaged in the design and development of 1,2,3-triazole based medicinal agents. However, the approach for development of such agents involving Huisgen’s cycloaddition reaction has gained immense importance. This manuscript covers different conventional and non-conventional approaches adopted for the synthesis of 1,2,3-triazole derivatives.