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Anais de Pesquisa Clínica e Laboratorial

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Serological Negative Cytomegalovirus Pneumonia Complicated with Bronchiolitis Obliterans Organizing Pneumonia in an Immunocompetent Patient: A Case Report

Chunxia Chen, Wan Chen, Xia Liu, Li Li and Luying Huang

A 63 year-old man presented with fever, cough, sputum and tachypnea. The latter deteriorated rapidly. A thoracic computed tomography (CT) scan revealed bilateral reticular shadows appearance and quickly spread around two lungs. Notably, CMV PCR was also negative. However, based on inclusion bodies found in lung tissue transbronchial biopsy (TBLB), the diagnosis of CMV pneumonia was confirmed. Lung biopsy showed bronchiolitis obliterans organizing pneumonia (BOOP). Following ganciclovir and steroid treatment, he made a gradually recovery and was discharged seven days later. This case demonstrated that CMV pneumonia may associate with bronchiolitis obliterans organizing pneumonia in an immunocompetent patient.